APAC Biotech is an Indian biotechnology company involved in research and development of advanced personalised cancer immunotherapies since 2009. The company's dendritic cell based personalised immunotherapy, APCEDEN®, is the first of its kind immunotherapy recognised and approved by the Indian Health Regulatory.
With more than a decade of research we understand that our immune system is powerful enough to fight cancer.
Today, our versatile research team of scientists and doctors are going deeper into creating unmatched personalised therapeutics to enhance the immune system further, enabling it to fight cancer better..
Enhancing The Immune System To Recognise & Attack Cancer Cells
Tumor cells disguise themselves in the body, thus escaping the immune system’s surveillance. These tumor cells continue to flourish and grow resulting in cancer metastasis (spreading of a tumor to other body parts). Immunotherapy is a new class of cancer treatment that works by harnessing the innate powers of the immune system to fight the cancer metastasis.
What do they do ?
Dendritic Cells are effective professional "Antigen Presenting Cells (APCs)" that express MHC I and MHC II molecules. In other words, their function is to recognise tumor proteins/infectious agents, engulf them and to express specific antigenic peptides derived from them on their surface.
Dendritic Cell based Therapeutic Cancer Vaccine
How Dendritic Cells fight Cancer ?
When
mature Dendritic Cells interact with resting T-Lymphocytes (Immune
cells responsible for attacking tumor cells), upon proper signalling,
they activate these resting T-lymphocytes to become "activated T-lymphocytes"
(CTLs, Cytotoxic-T lymphocytes). The CTLs now circulate in blood and
divide to proliferate and increase their number exponentially.
The CTLs can recognise the specific tumor cells (as educated by mature Dendritic Cells) and destroy them. APAC’s Dendritic Cell product APCEDEN®, utilises this process to make a "Dendritic Cell based Therapeutic Cancer Vaccine " for each cancer patient personalised according to their specific Cancer Tumor.
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